研究実績

2016

  •  Kim D, Dai J, Park YH, Yenwong Fai L, Wang L, Pratheeshkumar P, Son YO, Kondo K, Xu M, Luo J, Shi X, Zhang Z.Activation of EGFR/p38/HIF-1α is pivotal for angiogenesis and tumorigenesis of malignantly transformed cells induced by hexavalent chromium.J Biol Chem. 2016 May 25. pii: jbc.M116.715797. [Epub ahead of print]
  •  Kawakita N, Takizawa H, Kondo K, Sakiyama S, Tangoku A.Indocyanine Green Fluorescence Navigation Thoracoscopic Metastasectomy for Pulmonary Metastasis of Hepatocellular Carcinoma. Ann Thorac Cardiovasc Surg. 2016 May 17. [Epub ahead of print]
  •  Waka Sakai, Naoko Matsui, Mitsuyo Ishida, Takahiro Furukawa, Yoshimichi Miyazaki, Kouji Fujita, Ryosuke Miyamoto, Nobuaki Yamamoto, Wataru Sako, Kenta Sato, Kazuya Kondo, Yoshihiko Nishida, Takao Mitsui, Yuishin Izumi and Ryuji Kaji : Late-onset myasthenia gravis is predisposed to become generalized in the elderly, eNeurologicalSci, Vol.2, pp.17–20, 2016.

2015

  •  Wauthoz N, Bastiat G, Moysan E, Cie?lak A, Kondo K, Zandecki M, Moal V, Rousselet MC, Hureaux J, Benoit JP. Safe lipid nanocapsule-based gel technology to target lymph nodes and combat mediastinal metastases from an orthotopic non-small-cell lung cancer model in SCID-CB17 mice. Nanomedicine. 2015 Jul;11(5):1237-45. doi: 10.1016/j.nano.2015.02.010. Epub 2015 Mar 16.
  •  Kim D, Dai J, Fai LY, Yao H, Son YO, Wang L, Pratheeshkumar P, Kondo K, Shi X, Zhang Z. Constitutive activation of epidermal growth factor receptor promotes tumorigenesis of Cr(VI)-transformed cells through decreased reactive oxygen species and apoptosis resistance development. J Biol Chem. 2015 Jan 23;290(4):2213-24. doi: 10.1074/jbc.M114.619783. Epub 2014 Dec 4.
  •  Tamaki Otani, Hideki Otsuka, Kazuya Kondo, Hiromitsu Takizawa, M Nagata, M Kishida and Hirokazu Miyoshi : Utility of respiratory-gated small-animal PET/CT in the chronologic evaluation of an orthotopic lung cancer transplantation mouse model., Radiological Physics and Technology, Vol.8, No.2, pp.266–277, 2015.
  •  Hisashi Matsuoka, Kazuya Kondo, Hiromitsu Takizawa, Haruhiko Fujino, Etsuko Sakamoto, Junji Uchida, Koh Uyama, Hiroaki Toba, Koichiro Kenzaki, Shoji Sakiyama and Akira Tangoku : Comprehensive evaluation of the response of genes to the administration of the antitumor drug S-1 using a low density array, International Journal of Oncology, Vol.46, No.2, pp.569–577, 2015.
  •  Mitsuteru Yoshida, Shoji Sakiyama, Kazuya Kondo and Akira Tangoku : Thoracoscopic pericardial fenestration for effective long-term management of non-tuberculous mycobacterium pericarditis, General Thoracic and Cardiovascular Surgery, Vol.63, No.1, pp.49–51, 2015.  

2014

  •  Ali AH, Toba H, Sakiyama S, Yamamoto R, Takizawa H, Kenzaki K, Kondo K, Tangoku A. Holter ECG monitoring of sympathovagal fluctuation during bronchoscopy. Clin Respir J. 2014 Sep 5. doi: 10.1111/crj.12204. [Epub ahead of print] PMID: 25195956
  •  Mokhtar M, Tadokoro Y, Nakagawa M, Morimoto M, Takechi H, Kondo K, Tangoku A. Triple assessment of sentinel lymph node metastasis in early breast cancer using preoperative CTLG, intraoperative fluorescence navigation and OSNA. Breast Cancer. 2014 Jul 29. [Epub ahead of print] PMID: 25069434
  •  Frank C. Detterbeck, Kelly Stratton, Dorothy Giroux, Hisao Asamura, John Crowley, Conrad Falkson, , Pier Luigi Filosso, , Aletta A. Frazier, Giuseppe Giaccone, , James Huang, , Jhingook Kim, , Kazuya Kondo, ,Marco Lucchi, , Mirella Marino, , Edith M. Marom, , Andrew G. Nicholson, ,Meinoshin Okumura, , Enrico Ruffini, , Paul Van Schil, The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: Proposal for an Evidence-Based Stage Classification System for the Forthcoming (8th) Edition of the TNM Classification of Malignant Tumors. J Thorac Oncol. 2014;9: S65–S72
  •  Kazuya Kondo, Paul Van Schil, Frank C Detterbeck, Meinoshin Okumura, Kelly Stratton, Dorothy Giroux, Hisao Asamura, John Crowley, Conrad Falkson, Pier Luigi Filosso, Giuseppe Giaccone, James Huang, Jhingook Kim, Marco Lucchi, Mirella Marino, Edith M Marom, Andrew G. Nicholson, Enrico Ruffini, The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: Proposals for the N and M Components for the Forthcoming (8th) Edition of the TNM Classification of Malignant Tumors. J Thorac Oncol. 2014;9: S81–S87
  •  Faiz Y Bhora, David J Chen, Frank C Detterbeck, Hisao Asamura, Conrad Falkson, Pier Luigi Filosso, Giuseppe Giaccone, James Huang, Jhingook Kim, Kazuya Kondo, Marco Lucchi, Mirella Marino, Edith M Marom, Andrew G Nicholson, Meinoshin Okumura, Enrico Ruffini, Paul Van Schil, The ITMIG/IASLC Thymic Epithelial Tumors Staging Project: A Proposed Lymph Node Map for Thymic Epithelial Tumors in the Forthcoming 8th Edition of the TNM Classification of Malignant Tumors. J Thorac Oncol. 2014;9: S88–S96
  •  Andrew G. Nicholson, Frank C. Detterbeck, Mirella Marino, Jhingook Kim, Kelly Stratton, Dorothy Giroux, Hisao Asamura, John Crowley, Conrad Falkson, Pier Luigi Filosso, Giuseppe Giaccone, James Huang, Kazuya Kondo, Marco Lucchi, Edith M Marom, Meinoshin Okumura, Enrico Ruffini, and Paul Van Schil, The ITMIG/IASLC Thymic Epithelial Tumors Staging Project: Proposals for the T component for the Forthcoming (8th) Edition of the TNM Classification of Malignant Tumors. J Thorac Oncol. 2014;9: S73–S80
  •  Mizuno T, Okumura M, Asamura H, Yoshida K, Niwa H, Kondo K, Horio H, Matsumura A, Yokoi K; for the Japanese Association for Research on the Thymus. Surgical management of recurrent thymic epithelial tumors: A retrospective analysis based on the Japanese nationwide database.  J Thorac Oncol. 2014 Sep 22. [Epub ahead of print] PMID:25247341
  •  Kondo K. Therapy for thymic epithelial tumors. Gen Thorac Cardiovasc Surg. 2014 Jun 10. [Epub ahead of print] PMID:24913632
  •  Matsui N, Ohigashi I, Tanaka K, Sakata M, Furukawa T, Nakagawa Y, Kondo K, Kitagawa T, Yamashita S, Nomura Y, Takahama Y, Kaji R. Increased number of Hassall's corpuscles in myasthenia gravis patients with thymic hyperplasia. J Neuroimmunol. 2014 Apr 15;269(1-2):56-61. doi: 10.1016/j.jneuroim.2014.01.011. Epub 2014 Jan 28. PMID:24556356
  •  Mokhtar M, Kondo K, Takizawa H, Ohtani T, Otsuka H, Kubo H, Kajiura K, Nakagawa Y, Kawakami Y, Yoshida M, Fujino H, Sakiyama S, Tangoku A. Non-invasive monitoring of anticancer effects of cisplatin on lung cancer in an orthotopic SCID mouse model using [¹?F] FDG PET-CT. Oncol Rep. 2014 May;31(5):2007-14. doi: 10.3892/or.2014.3056. Epub 2014 Mar 5. PMID:24604559

2013

  •  Detterbeck FC, Asamura H, Crowley J, Falkson C, Giaccone G, Giroux D, Huang J, Kim J, Kondo K, Lucchi M, Marino M, Marom EM, Nicholson A, Okumura M, Ruffini E, van Schil P, Stratton K; Staging and Prognostic Factors Committee; Members of the Advisory Boards; Participating Institutions of the Thymic Domain. The IASLC/ITMIG thymic malignancies staging project: development of a stage classification for thymic malignancies. J Thorac Oncol. 2013 Dec;8(12):1467-73. doi: 10.1097/JTO.0000000000000017. PMID:24389429
  •  Mokhtar M, Kondo K, Namura T, Ali AH, Fujita Y, Takai C, Takizawa H, Nakagawa Y, Toba H, Kajiura K, Yoshida M, Kawakami G, Sakiyama S, Tangoku A. Methylation and expression profiles of MGMT gene in thymic epithelial tumors. Lung Cancer, Vol.83, No.2, pp.279-287, Dec, 2013. PMID:24388682
  •  Khasag N, Sakiyama S, Toba H, Yoshida M, Nakagawa Y, Takizawa H, Kawakami Y, Kenzaki K, Ali AH, Kondo K, Tangoku A. Monitoring of exhaled carbon monoxide and carbon dioxide during lung cancer operation. Eur J Cardiothorac Surg. 2013 Aug 2. [Epub ahead of print] PMID:23913245
  •  Yoshida M, Sakiyama S, Kondo K, Tangoku A. Thoracoscopic pericardial fenestration for effective long-term management of non-tuberculous mycobacterium pericarditis. Gen Thorac Cardiovasc Surg. 2013 Jun 27. [Epub ahead of print] PMID:23800889
  •  Toba H, Kondo K, Sadohara Y, Otsuka H, Morimoto M, Kajiura K, Nakagawa Y, Yoshida M, Kawakami Y, Takizawa H, Kenzaki K, Sakiyama S, Bando Y, Tangoku A. 18F-fluorodeoxyglucose positron emission tomography/computed tomography and the relationship between fluorodeoxyglucose uptake and the expression of hypoxia-inducible factor-1α, glucose transporter-1 and vascular endothelial growth factor in thymic epithelial tumours. Eur J Cardiothorac Surg.2013 Aug;44(2):e105-12. doi: 10.1093/ejcts/ezt263. Epub 2013 May 14. PMID:23674658
  •  Toba H, Kondo K, Miyoshi T, Kajiura K, Yoshida M, Kawakami Y, Takizawa H, Kenzaki K, Sakiyama S, Tangoku A. Fluoroscopy-assisted thoracoscopic resection after computed tomography-guided bronchoscopic metallic coil marking for small peripheral pulmonary lesions. Eur J Cardiothorac Surg. 2013 Aug;44(2):e126-32. doi: 10.1093/ejcts/ezt220. Epub 2013 Apr 18. PMID:23598353
  •  Yoshida M, Miyoshi T, Sakiyama S, Kondo K, Tangoku A. Pemphigus with thymoma improved by thymectomy: report of a case. Surg Today. 2013 Jul;43(7):806-8. doi: 10.1007/s00595-012-0272-z. Epub 2012 Aug 2. PMID:22855008

2012

  •  Toba H, Sakiyama S, Otsuka H, Kawakami Y, Takizawa H, Kenzaki K, Kondo K, Tangoku A. 18F-fluorodeoxyglucose positron emission tomography/computed tomography is useful in postoperative follow-up of asymptomatic non-small-cell lung cancer patients. Interact Cardiovasc Thorac Surg. 2012 Nov;15(5):859-64. doi: 10.1093/icvts/ivs368. Epub 2012 Aug 21. PMID:22914804
  •  Takizawa H, Kondo K, Toba H, Kajiura K, Ali AH, Sakiyama S, Tangoku A. Computed tomography lymphography by transbronchial injection of iopamidol to identify sentinel nodes in preoperative patients with non-small cell lung cancer: a pilot study. J Thorac Cardiovasc Surg. 2012 Jul;144(1):94-9. doi: 10.1016/j.jtcvs.2012.03.040. Epub 2012 Apr 14. PMID:22507846

2011

  •  Yoshida M, Kondo K, Nakanishi C, Tada T. Interventional study for improvement of lung cancer screening rate. J Med Invest. 2012;59(1-2):127-35. PMID:22450001 2011
  •  Ali AH, Takizawa H, Kondo K, Nakagawa Y, Toba H, Khasag N, Kenzaki K, Sakiyama S, Mohammadien HA, Mokhtar EA, Tangoku A. Follow-up using fluorescence bronchoscopy for the patients with photodynamic therapy treated early lung cancer. J Med Invest. 2011 Feb;58(1-2):46-55. PMID:21372486
  •  Ali AH, Takizawa H, Kondo K, Matsuoka H, Toba H, Nakagawa Y, Kenzaki K, Sakiyama S, Kakiuchi S, Sekido Y, Sone S, Tangoku A. 5-Aminolevulinic acid-induced fluorescence diagnosis of pleural malignant tumor. Lung Cancer. 2011 Oct;74(1):48-54. doi: 10.1016/j.lungcan.2011.01.031. Epub 2011 Feb 26. PMID:21353719
  •  Ali AH, Kondo K, Namura T, Senba Y, Takizawa H, Nakagawa Y, Toba H, Kenzaki K, Sakiyama S,Tangoku A. Aberrant DNA methylation of some tumor suppressor genes in lung cancers from workers with chromate exposure. Mol Carcinog. 2011 Feb;50(2):89-99. doi: 10.1002/mc.20697. Epub 2010 Nov 23. PMID:21229606
  •  Yano S, Yamada T, Takeuchi S, Tachibana K, Minami Y, Yatabe Y, Mitsudomi T, Tanaka H, Kimura T, Kudoh S, Nokihara H, Ohe Y, Yokota J, Uramoto H,Yasumoto K, Kiura K, Higashiyama M, Oda M, Saito H, Yoshida J, Kondoh K, Noguchi M. Hepatocyte growth factor expression in EGFR mutant lung cancer with intrinsic and acquired resistance to tyrosine kinase inhibitors in a Japanese cohort. J Thorac Oncol. 2011 Dec;6(12):2011-7. doi: 10.1097/JTO.0b013e31823ab0dd.

2010

  •  Kondo K. Tumor-node metastasis staging system for thymic epithelial tumors. J Thorac Oncol. 2010 Oct;5(10 Suppl 4):S352-6. PubMed PMID: 20859132.
  •  Matsui N, Nakane S, Saito F, Ohigashi I, Nakagawa Y, Kurobe H, Takizawa H, Mitsui T,Kondo K, Kitagawa T, Takahama Y, Kaji R. Undiminished regulatory T cells in the thymus of patients with myasthenia gravis. Neurology. 2010 Mar 9;74(10):816-20. PubMed PMID: 20211905.
  •  Kondo K. Invited commentary. Ann Thorac Surg. 2010 May;89(5):1619. PubMed PMID: 20417789.
  •  Kanematsu T, Hanibuchi M, Tomimoto H, Sakiyakma S, Kenzaki K, Kondo K, Bando H, Haku T, Yoneda K, Hirose T, Toyoda Y, Goto H, Sakaguchi S, Kinoshita K, Azuma M, Kakiuchi S, Kishi J, Azuma M, Tada H, Sumitomo M, Nishioka Y, Yano S, Sone S. Epidemiological and clinical features of lung cancer patients from 1999 to 2009 in Tokushima Prefecture of Japan. J Med Invest. 2010 Aug;57(3-4):326-33. PubMed PMID: 20847534.
  •  Toba H, Kondo K, Otsuka H, Takizawa H, Kenzaki K, Sakiyama S, Tangoku A. Diagnosis of the presence of lymph node metastasis and decision of operative indication using fluorodeoxyglucose-positron emission tomography and computed tomography in patients with primary lung cancer. J Med Invest. 2010 Aug;57(3-4):305-13. PubMed PMID: 20847531.
  •  Yoshida M, Kondo K, Tada T. The relation between the cancer screening rate and the cancer mortality rate in Japan. J Med Invest. 2010 Aug;57(3-4):251-9. PubMed PMID: 20847525.

2009

  •  Matsui N, Nakane S, Nakagawa Y, Kondo K, Mitsui T, Matsumoto T, Arisawa K, Kaji R. Increasing incidence of elderly onset patients with myasthenia gravis in a local area of Japan. J Neurol Neurosurg Psychiatry. 2009 Oct;80(10):1168-71. PubMed PMID: 19762910.
  •  Takizawa H, Kondo K, Toba H, Kenzaki K, Sakiyama S, Tangoku A. Fluorescence diagnosis of lymph node metastasis of lung cancer in a mouse model. Oncol Rep. 2009 Jul;22(1):17-21. PubMed PMID: 19513499.
  •  Yamai H, Sawada N, Yoshida T, Seike J, Takizawa H, Kenzaki K, Miyoshi T, Kondo K, Bando Y, Ohnishi Y, Tangoku A. Triterpenes augment the inhibitory effects of anticancer drugs on growth of human esophageal carcinoma cells in vitro and suppress experimental metastasis in vivo. Int J Cancer. 2009 Aug 15;125(4):952-60. PubMed PMID: 19462449.
  •  Yoshida M, Sakiyama S, Kenzaki K, Toba H, Uyama K, Takehisa M, Kondo K, Tangoku A. Functional evaluation of pallid mice with genetic emphysema. Lab Invest. 2009 Jul;89(7):760-8. Epub 2009 Apr 20. Erratum in: Lab Invest. 2009 Oct;89(10):1187. PubMed PMID: 19381131.
  •  Hirose Y, Kondo K, Takizawa H, Nagao T, Nakagawa Y, Fujino H, Toba H, Kenzaki K, Sakiyama S, Tangoku A. Aberrant methylation of tumour-related genes in thymic epithelial tumours. Lung Cancer. 2009 May;64(2):155-9. Epub 2008 Sep 7. PubMed PMID: 18778870.

2008

  •  Takizawa H, Kondo K, Matsuoka H, Uyama K, Toba H, Kenzaki K, Sakiyama S, Tangoku A, Miura K, Yoshizawa K, Morita J. Effect of mediastinal lymph nodes sampling in patients with clinical stage I non-small cell lung cancer. J Med Invest. 2008 Feb;55(1-2):37-43. PubMed PMID: 18319543.
  •  Kondo K. Optimal therapy for thymoma. J Med Invest. 2008 Feb;55(1-2):17-28. Review. PubMed PMID: 18319541.

2007

  •  Yoneda K, Ueno J, Nishihara S, Tsujikawa T, Morita N, Otsuka H, Furutani K, Nishitani H, Kondo K, Nishioka Y. Postprocessing technique with MDCT data improves the accuracy of the detection of lung nodules. Radiat Med. 2007 Dec;25(10):511-5. Epub 2007 Dec 25. PubMed PMID: 18085401.
  •  Hanibuchi M, Yano S, Nishioka Y, Miyoshi T, Kondo K, Uehara H, Sone S. Autofluorescence bronchoscopy, a novel modality for the early detection of bronchial premalignant and malignant lesions. J Med Invest. 2007 Aug;54(3-4):261-6. PubMed PMID: 17878675.
  •  Miyoshi T, Kondo K, Toba H, Yoshida M, Fujino H, Kenzaki K, Sakiyama S, Takehisa M, Tangoku A. Predictive value of thymidylate synthase and dihydropyrimidine dehydrogenase expression in tumor tissue, regarding the efficacy of postoperatively administered UFT (tegafur+uracil) in patients with non-small cell lung cancer. Anticancer Res. 2007 Jul-Aug;27(4C):2641-8. PubMed PMID: 17695427.
  •  Takizawa H, Kondo K, Sakiyama S, Monden Y. Computed tomography-guided drainage for large pulmonary bullae. Interact Cardiovasc Thorac Surg. 2004 Jun;3(2):283-5. PubMed PMID: 17670238.

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